Najnovejši podatki podpirajo nadaljnjo uporabo zaviralcev angiotenzinske konvertaze (zaviralcev ACE) ter antagonistov angiotenzina II (sartanov) med pandemijo COVID-19

/ Farmakovigilanca, Obvestila za javnost, Zdravila za uporabo v humani medicini

Najnovejši podatki podpirajo nadaljnjo uporabo zaviralcev angiotenzinske konvertaze (zaviralcev ACE) ter antagonistov angiotenzina II (sartanov) med pandemijo COVID-19

Nedavne opazovalne študije z zaviralci angiotenzinske konvertaze (zaviralci ACE) ter antagonisti angiotenzina II (sartani) ne kažejo, da bi ta zdravila vplivala na tveganje za okužbo z novim koronavirusom (virusom, ki povzroča COVID-19) ali imela negativen učinek na izid bolezni pri bolnikih s COVID-19.

Evropska agencija za zdravila (EMA) zato ponovno svetuje, da bolniki nadaljujejo z jemanjem teh zdravil v skladu z navodili zdravnika (glejte objavo JAZMP z dne 30.3.2020). Če imajo vprašanja ali skrbi glede zdravljenja, naj se posvetujejo s svojim zdravnikom.

Zaviralci ACE in sartani se najpogosteje uporabljajo za zdravljenje bolnikov z visokim krvnim tlakom, srčnim popuščanjem in boleznijo ledvic. V medijih in publikacijah je bila izražena zaskrbljenost glede učinkov teh zdravil pri bolnikih s COVID-19. Kot del stalnega spremljanja varnosti zdravil je bilo pregledanih 20 nedavno objavljenih študij o uporabi zaviralcev ACE in sartanov med pandemijo COVID-19, ki so pokazale, da najnovejši klinični dokazi teh pomislekov ne podpirajo.

V okviru EU regulativne mreže o zdravilih bodo EMA in pristojni nacionalni organi držav članic EU še naprej spremljali vse razpoložljive in nove podatke o uporabi zdravil v času pandemije COVID-19 in sodelovali z drugimi regulatorji in zadevnimi evropskimi in mednarodnimi organizacijami, da bi zagotovili zanesljive nasvete za varno uporabo zdravil.  Informacije o priporočilih o COVID-19 so dostopne na spletnih straneh EMA in JAZMP.

Povzeto po objavi EMA skupine COVID-19 EMA pandemic Task Force (COVID-ETF).

V primeru kakršnihkoli novih priporočil bomo javnost sproti obveščali.

Reference

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